How can a school be getting an epidemic of whooping cough if most of the students are vaccinated?












2















Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected students were vaccinated. How can this be?










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  • related

    – De Novo
    3 hours ago
















2















Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected students were vaccinated. How can this be?










share|improve this question























  • related

    – De Novo
    3 hours ago














2












2








2


1






Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected students were vaccinated. How can this be?










share|improve this question














Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected students were vaccinated. How can this be?







vaccination whooping-cough epidemic






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asked 5 hours ago









Tyler DurdenTyler Durden

18918




18918













  • related

    – De Novo
    3 hours ago



















  • related

    – De Novo
    3 hours ago

















related

– De Novo
3 hours ago





related

– De Novo
3 hours ago










1 Answer
1






active

oldest

votes


















5














Per the CDC:




A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.



In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.



CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.



Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.




Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.






share|improve this answer








New contributor




ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.





















  • Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.

    – De Novo
    3 hours ago











  • @DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.

    – ShadowRanger
    45 mins ago













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1 Answer
1






active

oldest

votes








1 Answer
1






active

oldest

votes









active

oldest

votes






active

oldest

votes









5














Per the CDC:




A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.



In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.



CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.



Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.




Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.






share|improve this answer








New contributor




ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.





















  • Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.

    – De Novo
    3 hours ago











  • @DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.

    – ShadowRanger
    45 mins ago


















5














Per the CDC:




A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.



In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.



CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.



Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.




Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.






share|improve this answer








New contributor




ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.





















  • Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.

    – De Novo
    3 hours ago











  • @DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.

    – ShadowRanger
    45 mins ago
















5












5








5







Per the CDC:




A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.



In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.



CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.



Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.




Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.






share|improve this answer








New contributor




ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.










Per the CDC:




A: Pertussis vaccines are effective, but not perfect. They typically
offer good levels of protection within the first 2 years after getting
the vaccine, but then protection decreases over time. Public health
experts call this ‘waning immunity.’ Similarly, natural infection may
also only protect you for a few years.



In general, DTaP vaccines are 80% to 90% effective. Among kids who get
all 5 doses of DTaP on schedule, effectiveness is very high within the
year following the 5th dose – at least 9 out of 10 kids are fully
protected. There is a modest decrease in effectiveness in each
following year. About 7 out of 10 kids are fully protected 5 years
after getting their last dose of DTaP and the other 3 out of 10 kids
are partially protected – protecting against serious disease.



CDC’s current estimate is that in the first year after getting
vaccinated with Tdap, it protects about 7 out of 10 people who receive
it. There is a decrease in effectiveness in each following year. About
3 or 4 out of 10 people are fully protected 4 years after getting
Tdap.



Keeping up-to-date with recommended pertussis vaccines is the best way
to protect you and your loved ones.




Given the size of the school and the effectiveness of the vaccine, it appears that ~30 infected kids is within what's expected.







share|improve this answer








New contributor




ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.









share|improve this answer



share|improve this answer






New contributor




ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.









answered 5 hours ago









ventsyvventsyv

1511




1511




New contributor




ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.





New contributor





ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.






ventsyv is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.













  • Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.

    – De Novo
    3 hours ago











  • @DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.

    – ShadowRanger
    45 mins ago





















  • Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.

    – De Novo
    3 hours ago











  • @DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.

    – ShadowRanger
    45 mins ago



















Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.

– De Novo
3 hours ago





Yes, outbreaks of this sort typically start with an unvaccinated index case and are able to spread because of the population of susceptible individuals, but end up infecting some vaccinated children. See my answer on Biology.SE, which discusses other outbreaks since 2000.

– De Novo
3 hours ago













@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.

– ShadowRanger
45 mins ago







@DeNovo: That said, pertussis/whooping cough seems to be an unusually bad case. The vaccine was adjusted for reduced side-effects (from whole cell to acellular) a couple decades ago, and the new version has lower efficacy, and it wanes rapidly.

– ShadowRanger
45 mins ago




















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